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KMID : 1040120160020040144
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Evidence and Values in Healthcare
2016 Volume.2 No. 4 p.144 ~ p.151
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Efficacy of vitamin and antioxidant supplements in prevention and treatment of diseases
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Myung Seong-Kwon
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Abstract
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According to a 2016 report from the Ministry of Food and Drug Safety of Korea (MFDS), the production quantity of vitamin and mineral supplements has increased from 141.5 billion won in 2014 to 2,079 billion won in 2015 by 47%. Also, many people believe that those supplements are beneficial for their health, and vitamin industries advertise vitamin and mineral products and promote those sales under the approval from the MFDS. Also, the previous several hundred observational epidemiological studies have reported that frequent consumption of fruit and vegetables rich in vitamins and antioxidants decreased the risk of chronic diseases such as cancer and cardiovascular diseases. However, since 2007, many randomized controlled trials (RCTs) and systematic reviews with meta-analyses of RCTs have indicated that vitamin or antioxidant supplementation showed null results or possible harms on our health including chronic diseases. This issue’s National Evidencebased Healthcare Collaborating Agency (NECA) Journal Club reviews the efficacy and safety of vitamin and antioxidant supplements in prevention and treatment of diseases based on the recent RCTs and meta-analyses.
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KEYWORD
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Vitamins, Dietary supplements, Randomized controlled trial, Meta-analysis
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